Season
Episode
- Episode 1: Gwen Stefani, Ben Platt, Zac Brown Band
- Episode 2: Demi Moore, Justin Hartley, Mark Ronson ft. Yebba
- Episode 3: Robert De Niro, Jameela Jamil, Bastille
- Episode 8: Natalie Portman, Henry Winkler, Robbie Robertson
- Episode 10: Joaquin Phoenix, Zoey Deutch
- Episode 12: Lupita Nyong'o, Dane Cook, Jay "Sinatraa" Won, Matthew "Super" DeLisi, The Avett Brothers
- Episode 13: Clive Owen, Elsie Fisher, Lewis Capaldi
- Episode 19: Michael Douglas, Kathryn Hahn, Jenny Lewis
- Episode 23: Reese Witherspoon, Rhett & Link, Daniel Humm
- Episode 31: Kristen Bell, Judd Apatow, Danny Brown
- Episode 35: Seth Meyers, Cobie Smulders, Tones and I
- Episode 40: Daisy Ridley, Tom Hiddleston, Michael Eric Dyson, Noah Cyrus, Leon Bridges
- Episode 41: Bernie Sanders, Katherin Langford, Gary Vaynerchuk
- Episode 43: Tracy Morgan, Brian Regan, Jason Aldean
- Episode 46: Kevin Delaney, Felicity Jones, Tomi Adeyemi, Burna Boy
- Episode 50: Hasan Minhaj, Charlie Puth
- Episode 51: Jon Hamm, Keri Russell, Gary Clark Jr.
- Episode 53: Michael B. Jordan, Sam Heughan, Lea Michele ft. Jonathan Groff
- Episode 54: John Lithgow, Liam Payne
- Episode 55: Helen Hunt & Paul Reiser, Dua Lipa, James Blake
- Episode 61: Will Smith, Patti Smith
- Episode 62: Martin Lawrence, Matthew Lopez, Kyle Soller, Karol G
- Episode 63: Selena Gomez, Charlie Hunnam, Stormzy
- Episode 66: The Cast of Schitt's Creek, Finn Wolfhard, Justin Willman
- Episode 67: Matthew McConaughey & Hugh Grant, Vanessa Hudgens, Ashley McBryde
- Episode 68: Ken Jeong, Kate Upton, Old Dominion
- Episode 71: Noah Centineo, Wendy Williams, Griselda
- Episode 72: Milo Ventimiglia, Guy Raz, Carmen Lynch
- Episode 73: Michael Strahan, Matt Bomer, Nick Thune
- Episode 74: Michael Bloomberg, Deepak Chopra, Rapsody ft. PJ Morton
- Episode 75: Blake Lively, Jameela Jamil, Roddy Ricch
- Episode 76: J. J. Watt, Louis Tomlinson
- Episode 77: Ewan McGregor, Fran Lebowitz, Mustard & Roddy Ricch
- Episode 78: Andy Samberg, Mary Elizabeth Winstead, Finneas
- Episode 79: Margot Robbie, Jeff Probst, Mura Masa & slowthai
- Episode 80: Claire Danes, Lana Condor, Lil Wayne
- Episode 81: RuPaul, Meghan Trainor
- Episode 82: Jennifer Lopez, Lil Rel Howery, Andre D Thompson
- Episode 83: Janet Jackson, Jane Levy, Jo Firestone
- Episode 84: Constance Wu, Backstreet Boys, Skip Marley & H.E.R.
- Episode 85: Ryan Seacrest, Zoë Kravitz, Jack Harlow
- Episode 86: Rosario Dawson, Logan Lerman, Megan Thee Stallion
- Episode 87: Steve Buscemi, Zoey Deutch, Justin Bieber & Quavo
- Episode 88: BTS: Subway Special
- Episode 90: David Beckham, Guy Fieri, Doja Cat
- Episode 91: John Mulaney, Bad Bunny
- Episode 93: Rachel Maddow, Pamela Adlon, Joji
- Episode 94: Kevin Bacon, Tan France, Taylor Tomlinson
- Episode 95: Hillary Rodham Clinton, Noah Schnapp, Jane Birkin, Iggy Pop
- Episode 101: Dr. Oz, Mandy Moore, Dane DeHaan
- Episode 106: At Home Edition: Trevor Noah, DJ D-Nice
- Episode 107: At Home Edition: John Legend
- Episode 108: At Home Edition: Niall Horan
- Episode 109: At Home Edition: Alec Baldwin, 5 Seconds of Summer
- Episode 110: At Home Edition: Tina Fey, Jose Andres
- Episode 111: At Home Edition: Kim Kardashian West, Jon Bon Jovi, Ryan Tedder
- Episode 112: At Home Edition: Demi Lovato, Jonathan Van Ness
- Episode 113: At Home Edition: Vice President Joe Biden, Andy Puddicombe, Marcus Mumford
- Episode 114: At Home Edition: Adam Sandler, Jessica Alba, Hot Country Knights
- Episode 115: At Home Edition: Miley Cyrus, Rachel Brosnahan, Lewis Capaldi
- Episode 116: At Home Edition: Lady Gaga, Andy Cohen, Billie Joe Armstrong
- Episode 117: At Home Edition: Justin Timberlake, Russell Wilson & Ciara, The Avett Brothers
- Episode 118: At Home Edition: Taraji P. Henson, Dua Lipa
- Episode 119: At Home Edition: Mike D & Ad-Rock, Anna Kendrick
- Episode 120: At Home Edition: Kerry Washington, Andrew Rannells, Anderson .Paak & The Free Nationals
- Episode 121: At Home Edition: Blake Shelton, Kenan Thompson, Gwen Stefani
- Episode 122: At Home Edition: Michael Shannon, JJ Watt, Rita Ora
- Episode 123: At Home Edition: Pharrell Williams, Millie Bobby Brown
- Episode 124: At Home Edition: Chelsea Handler, Kelly Clarkson, Michael McDonald
- Episode 125: At Home Edition: Hugh Jackman, Rose Byrne, Kesha
- Episode 126: At Home Edition: Melissa McCarthy & Octavia Spencer, Megan Thee Stallion, Dan White
- Episode 127: At Home Edition: Halle Berry, Russell Westbrook, Meghan Trainor
- Episode 128: At Home Edition: LL Cool J, Dr. Jane Goodall, Kate Tempest
- Episode 129: At Home Edition: Alex Rodriguez, Rhett & Link, Tones and I
- Episode 130: At Home Edition: Jonas Brothers, Lester Holt, Charli D'Amelio, Chvrches
- Episode 131: At Home Edition: Kate Hudson, Alessia Cara
- Episode 132: At Home Edition: Ricky Gervais, Billy Porter, The Lumineers
- Episode 133: At Home Edition: Shailene Woodley, Maluma, Thom Yorke
- Episode 134: At Home Edition: Vince Vaughn, Gigi Hadid, Maluma
- Episode 135: At Home Edition: Jon Hamm, Brene Brown, Will Ferrell, Kristen Wiig, Jack Gyllenaal, Hailee Steinfeld
- Episode 136: At Home Edition: Ashton Kutcher, Mila Kunis, Evan Rachel Wood, Annie Lennox
- Episode 137: At Home Edition: Ryan Reynolds, Karlie Kloss, Ezra Koenig
- Episode 138: At Home Edition: Gov. Andrew Cuomo, Gabrielle Union, Brad Paisley
- Episode 139: At Home Edition: Queen Latifah, Pete Davidson, Judd Apatow, James Taylor
- Episode 140: At Home Edition: Mark Ruffalo, Bill Murray & Guy Fieri, Miranda Lambert
- Episode 141: At Home Edition: Seth MacFarlane, David Chang, Lady Antebellum
- Episode 142: At Home Edition: Ethan Hawke, Elle Fanning, Maroon 5
- Episode 143: At Home Edition: David Spade, Kathryn Hahn, Horatio Sanz, The Killers
- Episode 144: At Home Edition: Chris Evans, Mo Willems, Kane Brown
- Episode 145: At Home Edition: Dwayne Johnson, Daveed Diggs, The Head and The Heart
- Episode 146: At Home Edition: Arnold Schwarzenegger, Cole Sprouse, Billy Corgan
- Episode 147: At Home Edition: Ben Stiller, Hannah Gadsby, Tim McGraw
- Episode 148: At Home Edition: Anthony Anderson, Michelle Dockery, Gary Clark Jr.
- Episode 149: At Home Edition: Sofia Vergara, Steve Coogan & Rob Brydon, Courtney Barnett
- Episode 150: At Home Edition: Jennifer Lopez, Henry Winkler, Twenty One Pilots
- Episode 151: At Home Edition: Derrick Johnson, Don Lemon, Jane Elliott, The Roots and Bilal
- Episode 152: At Home Edition: Kareem Abdul-Jabbar, Phoebe Robinson, W. Kamau Bell
- Episode 153: At Home Edition: Senator Kamala Harris, Talib Kweli, Roy Wood Jr, The Roots & Yim Yames
- Episode 154: At Home Edition: Senator Bernie Sanders, Dr. Bernice A. King, Wyatt Cenac
- Episode 155: At Home Edition: John Oliver, Spike Lee, Benee ft. Gus Dapperton
- Episode 156: At Home Edition: Queer Eye's Fab Five, Christian Slater, Sia
- Episode 157: At Home Edition: Robert De Niro, James Blake, Lenny Kravitz
- Episode 158: At Home Edition: Anthony Mackie, David Dobrik, Avril Lavigne
- Episode 159: At Home Edition: Kevin Bacon, Aunjanue Ellis, Sarah Cooper, Christine and the Queens
- Episode 160: At Home Edition: Martin Short, Bashir Salahuddin & Diallo Riddle, Randy Newman
- Episode 161: At Home Edition: Gwyneth Paltrow, Zachary Quinto, Alec Benjamin
- Episode 162: At Home Edition: Sean Penn, Robin DiAngelo, Weezer
- Episode 163: At Home Edition: Don Cheadle, Reverend Al Sharpton, Luke Bryan
- Episode 164: At Home Edition: John Legend, Mike Birbiglia
- Episode 165: At Home Edition: Lin-Manuel Miranda, Kenya Barris, Michael Stipe & Big Red Machine
- Episode 166: At Home Edition: Russell Crowe, Ben Platt, Brittany Howard
- Episode 167: At Home Edition: Shaquille O'Neal, John Lithgow, Ozuna
- Episode 168: At Home Edition: Pierce Brosnan, Nicole Richie, Blackpink
- Episode 169: At Home Edition: Charlize Theron, Gov. Andrew Cuomo, Little Big Town
- Episode 170: At Home Edition: Colin Jost, Rep. Val Demings, Davido
- Episode 172: Jim Carrey, Jenny Slate, Luke Combs
- Episode 173: David Schwimmer, Alison Brie, Jimmy Buffett
- Episode 174: Andy Samberg, Jose Andres, Perfume Genius
- Episode 175: Cameron Diaz, Mayor Keisha Lance Bottoms, Kygo with OneRepublic
- Episode 176: Will Arnett, Michaela Coel, H.E.R.
- Episode 177: Mike Tyson, Adam Devine, Chronixx
- Episode 178: Michael Che, Megan Rapinoe, Angel Olsen
- Episode 179: Ice T, Jack Whitehall, Charlie Wilson
- Episode 180: Seth Rogen, Chiwetel Ejiofor, Alanis Morissette
- Episode 181: Common, Matisse Thybulle, Rufus Wainwright
- Episode 182: Jesse Eisenberg, Blake Griffin, Gracie Abrams
- Episode 183: Jamie Foxx, Tig Notaro, Black Pumas
- Episode 184: Matthew McCounaughey, Jaden Smith
- Episode 185: Bryan Cranston, Julia Garner, Surfaces
- Episode 186: Orlando Bloom, Cecily Strong, Trey Anastasio
- Episode 187: Joseph Gordon-Levitt/Paula Pell/Jessie Reyez
- Episode 188: Seth Meyers, David Blaine, Burna Boy
- Episode 189: Tiffany Haddish, Jurnee Smollett, Orville Peck & Shania Twain
- Episode 190: Hugh Jackman. Lili Reinhart, Buju Banton
- Episode 191: Tyler Perry, Maisie Williams, Trevor Daniel
- Episode 192: Rachel Maddow, Fred Armisen, Tiwa Savage
- Episode 193: Joel McHale, Big Sean
- Episode 194: Kevin Hart, Josh Charles, CHIKA
- Episode 195: Miley Cyrus
- Episode 196: Kelly Clarkson, Joy Reid, The Flaming Lips
- Episode 197: Jude Law, Maya Erskine and Anna Konkle, Summer Walker
- Episode 198: Ewan McGregor, Willie and Bobbie Nelson, Kesha
- Episode 199: Sharon Stone, Shaquille O'Neal, Kylie Minogue
- Episode 200: Seth MacFarlane, Evan Rachel Wood
- Episode 201: Jessica Alba, Jack Huston, Keith Urban
The Tonight Show Starring Jimmy Fallon Season 7 At Home Edition: Martin Short, Bashir Salahuddin & Diallo Riddle, Randy Newman
After Jay Leno's second retirement from the program, Jimmy Fallon stepped in as his permanent replacement. After 42 years in Los Angeles the program was brought back to New York.
